Restylane is very effective in smoothing out and filling in bothersome wrinkles and lines, particularly in the lower part of the face. It has several advantages over other filler-type materials such as collagen; it lasts longer and causes very little adverse reaction. It is easy to administer (injected through a small needle), and once its effectiveness has diminished six months to a year later, the body safely absorbs it.

Restylane and Botox (botulinum toxin) often are used in a complementary fashion. While Restylane is best for the lower face, Botox is great for wrinkles that occur in the upper face – crow’s feet or the vertical frown lines between the eyebrows – because it paralyzes muscle and nerve endings, stopping the skin from wrinkling.